Using Stem Cells to Improve Surgical Outcomes for Rotator Cuff Injuries

Investigating novel stem cell-based therapies for rotator cuff repair

Hospital for Special Surgery
New York City, NY Dr. Christopher L. Mendias

The National Stem Cell Foundation is partnering with the Orthopaedic Research and Education Foundation to support the work of Dr. Christopher Mendias at the Hospital for Special Surgery in New York City.

Rotator cuff disease is a frequent and debilitating upper extremity injury. Even after surgical repair, patients with chronic rotator cuff tears often fail to return to full function, and experience persistent pain and disability.

Cells harvested from the stromal vascular fraction of subcutaneous adipose tissue (SVFCs) have been shown in preclinical studies to possess the ability to enhance the regeneration of musculoskeletal tissues.

Dr. Mendias is conducting a phase II clinical trial to determine if this promising and practical autologous cell therapy can improve outcomes for patients with chronic rotator cuff tears who undergo surgical repair.